NATURAL OR SYNTHETIC MARIJUANA - WHAT'S BEST?
Should I take synthetic marijuana or natural, and why?
Natural Cannabinoids are definitely not the same as synthetic. Pharmaceutical companies and so-called orthodox medical doctors prefer to prescribe drugs found in the drug store - which are almost invariably synthetic preparations. The only reason that the medical industry focuses almost exclusively because they are patentable, they contain one ingredient, which is easy to isolate their properties - the cause and effect. At the end of the day, above all else, synthetic medicines are very profitable, with more than $1 trillion in sales per annum.
What's lost in the equation is your health and wellness. It turns out, there is no scientific basis for the preference for synthetic compounds. In the case of cannabinoids and whole herb cannabis, not one single study exists that suggests that synthetics are superior to the real thing. If you can find one email email@example.com. In fact, there are more than fifty peer reviewed studies, animal and human studies suggest that synthetic cannabinoids are, in fact, far inferior to whole cannabis medicines.
Each top-100 drug has a billion $ or more in sales per per year. Patenting a drug means a drug company has a monopoly on the market for decades. Meanwhile, natural medicines cannot be patented and this is the sole reason the pharmaceutical industry - and their compliant physicians - do not prescribe natural remedies, herbals, vitamins and health foods. Why? There is no profit in it. It is as simple as that.
"Withdrawal from synthetic cannabinoids are perceived to causes effects similar to those experienced with withdrawing from the use of narcotics."
Pharmaceutical recognize the trend of the public toward organic and market their synthetic product as natural-like. However, there is evidence, consistent with other pharmaceuticals, like synthetic opiates, synthetic cannabinoids can do more harm than good
Most people know that it is the THC in cannabis that makes people high. Growers selected plants and seed that tended to produce more THC with a more potent high. Over generations the THC content of weed went from 3-12% to 15 to 30%, depending on the variety. While THC is quite medicinal, some people that could use the medicinal effects don't respond well its psychoactive effects.
Most of the cells of mammals, including human possess receptors that control the function of most bodily systems, which include the nervous system, muscular system, brain function, cardiovascular system. These receptors are activated, dialed up and dialed down by compounds produced by the body called endocannabinoids. If the body does not produce enough or too much of these endocannabinoids, spasm, anxiety, stress, depression, nervous and immune system response can result. It was discovered back in the 1960's that cannabis could tap into this natural body system, and substitute for natural endocannabinoids. This is the scientific medical basis for cannabis based medicines.
Synthetic cannabinoids are made in the lab and they can be more powerful than natural ones. Their reaction with receptors can be over the top, producing psychosis, spasms, and more, which is the case with Spice, a terrible mixture of synthetic cannabinoids, speed and god knows what. Imagine drinking a beer that was 1000x stronger than usual, or a chilli pepper 1000x stronger than usual, or driving your car 1000x the normal speed. You get the idea. While natural cannabinoids are inherently safe, multiplying their anti anxiety, anti spasm and other effects by thousand results understandably in a sad, tragic scene, where the user turns to jelly, cannot speak, body turns to rubber.
"Of the hundred or so synthetic cannabinoids produced by researchers and black-chemists, only Marinol is approved by FDA and is available by prescription in the United States."
To be clear, commercially available synthetic pharmaceutical cannabinoids are simply an analogue of THC and are not dangerous, but patients prefer the real thing more than 95% of the time, in almost all studies.
Ingestion of synthetic cannabis can lead seizures, hallucinations, convulsions, mental illness, schizophrenia and stroke.
A survey of 14,000 subjects showed that 93% prefer cannabis over synthetics, and that synthetic cannabinoids have more negative effects; paranoia and next-day hangovers. In another study, 2.4% of people using synthetic pharmaceutical cannabis required emergency medical attention. To be fair, emergency rooms take in their fair share of THC green-out patients. Both synthetic and natural overindulgence of THC has accounted for zero documented fatalities.
MMJDoctorOnline Notes: Most medical professionals with knowledge about cannabis based medicines recommend natural medical cannabis to treat their patient's conditions and symptoms. In California and Nevada, a medical doctor's recommendation is required to purchase cannabis based medicines from dispensaries, delivery services, cannabis clinics, cooperatives and other vendors. The process of getting a 420 evaluation, Cannabis ID Card, or a grow permit is easy. The online process takes only a few minutes to complete and your application can be approved the same day. Patients are not required to pay if they are not approved.
Cannabidiol (CBD) Frequently Asked Questions. There are a couple of questions about cannabidiol (CBD) that we get asked more frequently, so we decided to put together a list of CBD FAQs for those of you who are still new to this topic and want to learn more about this cannabinoid, its properties and effects....
When synthetic cannabinoid blends first went on sale in the early 2000s, it was thought that they achieved an effect through a mixture of natural herbs. Laboratory analysis in 2008 showed that this was not the case, and that many in fact contain synthetic cannabis that act on the body in a similar way to cannabis naturally found in cannabis, such as THC or CBD.
A large and complex variety of synthetic cannabis, most often cannabicyclohexanol, JWH018, JWH073, or HU210, are used in an attempt to avoid the laws that make cannabis illegal, making synthetic cannabinoid a designer drug. They have been sold under various brand names, online, in head shops, and other stores. Studies have associated synthetic cannabinoid use with psychotic episodes days after use, some of which have resulted in death
These Synthetic cannabis have been compared with the psychoactive compound, Δ-9-tetrahydrocannabinol (THC), found in cannabis. On the molecular level, they are potent cannabinoid receptor agonists that also may have affinity for other types of receptors. Reported symptoms of toxicity include anxiety, agitation, paranoia, hallucinations, tachycardia, hypertension, excessive sweating, nausea, and vomiting.
Overdoses of synthetic cannabis can cause panic attacks and psychosis and lead to tragic results. In 2010, an Iowa teen smoked K2 with some friends, and then reportedly told them he was "going to hell" and went home, where he shot and killed himself. In another case, a 19-year-old in Illinois died when his car jumped a retaining wall at an estimated speed of 100 mph, flew 15 feet, and crashed into a house. ...
Israeli scientists Shimon Ben-Shabat and Raphael Mechoulam first described the basic idea of the entourage effect - that cannabinoids within the cannabis plant work together - and possess synergy, and affect the body in a mechanism that mimics to the body’s own endocannabinoid system.
Mechoulam et.al. ideas are the foundation for a relatively controversial idea within pharmacology community, and not so controversial idea among independent scientists, that in the majority of cases whole plant extractions serve as better therapeutic agents than individual cannabinoid extractions. The entourage effect theory is expanded upon by other researchers including Wagner and Ulrich-Merzenich, who define the four basic mechanisms of whole plant extract synergy as follows.
affects multiple targets within the body
improves the absorption of active ingredients
overcomes bacterial defense mechanisms
minimizes adverse side effects